Nutrition Science

Research Pipeline

The Alliance for Potato Research and Education (APRE) was established in June 2011 to advance the scientific understanding of the role potatoes play in promoting health, including the role of potatoes on cardiometabolic health, healthy dietary patterns, and healthy lifestyles (with an emphasis on athletic performance and life stages). These summaries highlight research currently underway.


Impact of a Low Glycemic Load (GL) Diet Containing Potatoes on Body Composition and Cardiometabolic Health in Subjects with Metabolic Syndrome (MetS)

University of Arkansas

A clinical trial investigating the short- and long-term effects of consuming various forms of potatoes as part of low GL diets in MetS subjects on markers of cardiometabolic health, such as blood glucose and cholesterol levels. Participants will consume at least four potato meals per week as part of a low GL meal, either prepared white potatoes or processed fried potatoes.

Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults with Metabolic Syndrome (MetS)

The Ohio State University

A clinical trial examining potatoes in a dietary pattern based on the 2015-2020 Dietary Guidelines for Americans (DGA), in patients with MetS. The study will assess how potato resistant starch impacts the gut microbiome, which can impact cardiovascular health.

Efficacy of Potato Resistant Starch (RS) on Improving Gut Microbiota Composition, Inflammatory Profile, and Insulin Signaling in High-Fat Fed Rats

University of Georgia

An animal study conducted in rodents that assessed the impact of potato RS supplementation on changes in gut microbiota composition. The study looked at gastrointestinal function, inflammatory signaling and insulin function to understand the role of potato RS as a potent prebiotic, with potential therapeutic benefits against obesity and its associated comorbidities.

Potato Product Form Impacts In Vitro Starch Digestibility and Glucose Transport but Only Modestly Impacts 24h Blood Glucose Response in Humans

North Carolina State University

A trial with pre-clinical and clinical components that assessed the digestive release and accessibility of white potato phenols, as well as the ability of potato phenolics to impact starch digestion and glucose uptake and transport. The study also assessed the impact of potatoes on the gut microbiome.

Potato Consumption and Risk of Chronic Disease: Qualitative Gap Analysis

Tufts University

An evidence mapping project summarizing published data related to potato intake and biomarkers of health and disease over the past 10 years. The analysis will include interviews with key nutrition and health experts to identify gaps, strengths and weaknesses of currently published trials in an effort to make recommendations to help improve future studies.

The Effect of Potatoes on Markers of Cardiometabolic Health

Pennsylvania State University

A clinical trial that compared the effect of daily potato consumption to a fixed amount of refined cereals and grains in healthy weight individuals. The study looked at the following markers of cardiometabolic health; fasting glucose levels, insulin sensitivity, blood pressure, lipids and lipoproteins, arterial stiffness, body weight and dietary intake, as well as diet quality.

Effects of Potato Resistant Starch (RS) Intake on Insulin Sensitivity, Related Metabolic Markers and Satiety in Overweight or Obese Men and Women

Center for Metabolic & Cardiovascular Health

A clinical trial comparing acute (one day) potato intake with carbohydrate-matched foods low in fiber and RS. Participants will consume roughly two potatoes per day, in different meal forms containing 15 grams of RS. The study looks at potatoes’ impact on postprandial insulin sensitivity, markers of satiety and free fatty acid levels in overweight or obese adults.

Potato Intake and Risk of Cardiovascular Disease in a Large Norwegian Cohort

Norwegian University of Science and Technology

An epidemiological study investigated the association between potato intake and risk of all-cause mortality and cardiovascular disease mortality. The study also determined there is no association or a very weak association between boiled potatoes and an increased risk of type 2 diabetes, hypertension, cardiovascular disease-related hospitalization and obesity.

Healthy Adolescent Dietary Patterns for Minimizing Cardiometabolic Risk Include Regular Potato Consumption

Boston University

An epidemiological study evaluating the contribution of potato consumption, as part of a healthy diet, to changes in body fat and blood pressure throughout adolescence in young girls. The study will also evaluate the effects of potato consumption on the risk of elevated glucose levels or dyslipidemias at the end of adolescence.

Cardiometabolic Health Outcomes Associated with Potato Consumption in Framingham Study Adults

Boston University

An epidemiological study examining the effects of potato consumption (whole potatoes and French fries) on cardiometabolic risk in adults, while accounting for differences in diet patterns and other lifestyle habits. The study will use prospective data from the Framingham database to look at the impact of high versus low potato intake on blood pressure, blood glucose levels and serum lipids over 15 years.

How Gut Microbiota Profiles Influence Potato Resistant Starch (RS) Response in Overweight Females

Texas Woman’s University

Continuation of an ongoing trial looking at the impact of Russet potatoes on the gut microbiome. Preliminary data indicates potato RS decreases glycemic response, and this study will expand on these initial findings to look at the association between subjects’ gut bacteria profile and glycemic response. The association between diet and physical activity and the gut microbiome will also be explored.

Effects of Potatoes on Potassium Retention and Blood Pressure in Mildly Hypertensive Men and Women

Purdue University

A clinical trial investigating whether potassium retention from potatoes is equal to or better than that of potassium supplements in hypertensive adults. The primary outcome variables in this study include blood pressure and the impact of potassium on bone health, as measured by acid-base balance and bone calcium retention.

Effects of White Potato Consumption on Measures of Cardiometabolic Health in Individuals with Type 2 Diabetes Mellitus

Florida State University

A clinical trial with an epidemiologic component examining whether daily consumption of white potatoes contributes to improvements in cardiometabolic health and diet quality in subjects with type 2 diabetes, compared to a calorie-matched refined grain group. Epidemiological data from the National Health and Nutrition Examination Survey (2010-2016) will be used to assess dietary intakes, as well as the most common potato preparation methods among individuals with type 2 diabetes.

Effect of Potato Form and Consumption Pattern on Acute Glycaemia and Glucose Kinetics in Individuals with Type 2

University of Surrey, United Kingdom

A clinical trial among adults with type 2 diabetes investigating the impact of consuming different white potato preparations (boiled whole, boiled mashed, and baked French fries), at recommended portion levels, as part of a mixed meal. The study will evaluate how various potato forms impact post-meal metabolic responses (e.g., plasma glucose, insulin and triglyceride levels).

Potato Consumption in Plant Protein Based Meals on Cardiometabolic Risk

University of Toronto

A clinical study investigating the impacts of fried potatoes, as part of plant-based diets, on various cardiometabolic risk factors in overweight non-vegetarian adults. The researchers will examine whether daily consumption of a vegetarian meal with fried potatoes leads to more effective weight management, compared to consuming the meal with rice or pasta.

Developing healthy potato-based meals with delayed gastric emptying, prolonged energy supply, and modulated postprandial glycemic response in healthy adults

Singapore Institute of Food and Biotechnology Innovation (SIFBI)

A randomized controlled trial evaluating if the sequence of food intake can better manage after-meal blood sugar control, and prolong the energy supply from potatoes, as part of a healthy meal. Participants will be instructed to eat leafy vegetables first, followed by meat and ending with potato foods. Blood sugar, insulin, GLP-1 gut hormone and satiety will be measured to assess digestion and gastric emptying time of the potatoes.

Frequency of Boiled Potato Consumption and All-Cause and Cardiovascular Disease Mortality in the Prospective Population-Based HUNT Study

Norwegian University of Science and Technology

An epidemiological study assessing the association between potato consumption and mortality in a Norwegian population. Researchers used longitudinal population-based data to determine whether frequency of boiled potato intake was related to all-cause mortality or cardiovascular disease mortality.


Potato Consumption and Energy Balance: A Randomized, Controlled, Clinical Trial

Indiana University

A clinical trial determining whether a difference exists in weight gain with daily potato consumption versus a calorie-matched snack of almonds. The outcomes will provide additional data to better understand the impact of dietary complexity on carbohydrate metabolism and weight change.

Determination of the Impact of Cooking Method on Quality of Potato Protein as Determined Using In Vitro Approaches

University of Manitoba

An in vitro investigation of factors impacting the quality of potato protein in Russet potatoes subjected to various cooking methods: boiled, baked, fried and microwaved. The study will also compare protein quality of potatoes to other protein sources, such as casein and soy. The use of an artificial gut model will allow for measurements of glycemic index and other related parameters, like protein digestion rates and potassium bioavailability.

Optimizing Potato Consumption to Enhance Cardiometabolic Health in Adults

Pennington Biomedical Research Center, Louisiana State University

A clinical trial comparing the effect of healthy eating patterns containing potatoes and lean meat mixed meals to healthy eating patterns containing pulses and lean meat mixed meals. The study will include potatoes in various forms (e.g., salad, cakes, soup, wedges) and examine the following markers of cardiometabolic health in overweight and obese, insulin-resistant adults: glycemic response, lipid profile, and an inflammatory biomarker.

Long-Term Effects of a Potato-Based Food Pattern vs a Rice/ Pasta-Based Food Pattern on Fasting and Postprandial Cardiometabolic Health

Maastricht University

A clinical trial assessing the effect of a potato-based, carbohydrate-rich, healthy eating pattern, compared to the same meal with white rice or pasta in overweight and obese healthy adults. The study will measure changes in blood sugar concentration, along with glucose and lipid metabolism endpoints, all of which are considered well-established markers for cardiovascular disease.

Effects of Potatoes, Prepared in Various Forms, in the Dietary Approaches to Stop Hypertension (DASH) Diet on Blood Pressure in Adults with Type 2 Diabetes

Texas Tech University

A clinical trial examining the effects of following a DASH eating plan that either includes five servings of fried potatoes, five servings of non-fried potatoes, or no potatoes each week, for five weeks, on blood pressure, other anthropometric measures and subjective feelings of hunger and satiety among adults with type 2 diabetes. All study participants will consume the same standard DASH eating plan for a three-week period, followed by a random assignment to one of the test DASH eating plans.



Potato-Supported Strategies to Increase Carbohydrate Oxidation, Race Economy and Performance during Endurance Exercise

Australian Institute of Sport

A clinical trial investigating whether a relationship exists between increased carbohydrate oxidation and improved exercise economy and performance in elite athletes. The results will help to determine if specific feeding strategies, in the form of potato-based meals, can increase glycogen stores in endurance athletes to higher levels than conventional carbohydrate loading.

Anabolic Properties of Potato-Derived Protein

Maastricht University

A clinical trial assessing the impact of 30 grams of potato protein on muscle protein synthesis rates at rest, as well as during recovery from exercise, in young healthy males. The study data will help to determine how well potato protein can support muscle protein synthesis and muscle reconditioning following exercise.

A Short-Term Potato-Enriched Diet to Support Muscle Accretion and Promote Substrate Metabolism Adaptations in Recreationally Active Individuals

Swinburne University of Technology, Australia

A clinical trial investigating the effect of a potato-enriched, non- animal protein diet, compared to a diet with protein derived from only animal-based sources. The study will measure differences in muscle protein response to exercise in healthy, young males and will include potatoes in various forms (e.g., mashed, baked, chips), with 50% of daily protein derived from potatoes in the non-animal protein diet for a two- week period.


Looking to contribute to potato science?
APRE's research program was created to extend the understanding of the nutritional value of potatoes, while adhering to guidelines that support sound and credible research through industry funding. To receive email announcements on our annual grant and fellowship programs, sign up below.
Keep Updated